You can only replace a regular ability for a regular ability, or an ult for an ult. What would you do?
with 
Valkyrie on his E.
I am a giant full ap void lizard flying at you dropping bombs to cc and oneshot your face. Deal with it.
Fuh Queue9 votesI'd replace Alistars ult with Yasuo's ult...
Lyndris2 votesfun stuff*[slayer-pantheon-thumbs]*
HeimerLmao3 votes
E with 
q
TheSequelsRBad1 votesYeah, that would be a pretty good one...
Illâoi Evê Siôn1 votesOr E with 
E
agbudar2 votes
ult with 
idk i think it would be fun
E with 
E
seems like it would fit the bear better idk
AlienPrimate2 votes
slow pool replaced with Galio's shield.
He now does damage by getting chased and gets healed by being hit.
Lyndris1 votesXD loool
Voidas12 votesSinged passive with Veigars passive
420 grams1 votesTryndamere q with ezreal e. Now I have 2 gap closers and a slow
JVP151 votesJust imagine
E becomes 
E.
I can see the combo now... E to stun, W,Q,P,R, ded.
Golden Tager X1 votes
With 
E for his e
Hyper mobile juggernaut with 350 ad incoming.
MistroTTC1 votesI think you mean Riven's Q, her E is the dash with a shield and her Q is the multiple dashes.
Lyndris1 votes
passive for 
passive (little flowers instead though)
or if passives aren't allowed
q for 
q
Blue Moon Wolf1 votes
's E with 
's W.
boo9101 votesany ult with karthus ult
Darthsteele1 votesUrgot q with ez q but still have the e lock it on
DuskDaUmbreon1 votes
's W with 's hookshot. You thought you could escape his poison? You thought you could catch him? THINK AGAIN!
's R with 
's R. You cannot kill the million-stack doggo.
's W with 
's E. She now has ALL of League's mobility, and you can't do anything about it.
's Preparation (or 
's W) with 
's E. You now cannot stop her (them).
's passive with 
's passive. He now is the million and twelve stack doggo. (For moar rage, give him 
's passive)
's R with 's R. They can actually ult in a team fight without saving the enemy team, now! And they can actually survive a fight!
Not an ability, but give 
a Scuttle crab skin. His play rate will spike to around 70%.