When I'm playing Garen against an enemy Riven, and she tries to poke me mindlessly with her QQQ
....so I responded with a simple E while hitting W and then Ignite, and grabs first blood.
My reaction:
http://33.media.tumblr.com/ed91cade5f8c236d162174eca45e7cb7/tumblr_n6i2l5siJJ1qg4e0wo4_r1_500.gif