Can we just get rid of the Runes?
The complexity of this game should come from the champs we have to pick, the counter pick etc. That's enough, we don't need any additional configurations beyond that. I've never seen any value complicating the game through Runes, masteries or any other crap that Riot comes up with. It will make balancing the champs far easier and will lead to more enjoyable game play. That is ultimately what the average player wants, we don't want to have to go through a Rune process every game.
Call me a Bronze player, but year before last for the mastery system I hardly ever looked/picked them. I just went online, copied 10 presets down from some yahoo who posted a guide and I played those 10 champs. Got me to gold with no problems.
Another point to this, I shouldn't have to go online to a website before the game to see what 'configurations' a player has chosen.. it's just stupid game design.