against yes, because you get free kill as syndra... with no, because you give free kills to annie...
Q 11 seconds, falls near an enemy and the time it needs to fall , the enemy is gone and you lose a chunk of damage. W 15 seconds, on a low range location (where you are currently ) with a small MS buff for a short period, which causes you to Lose damage yet again. Her "E" use alone is nothing, but people keep thinking that shunpoing in 50 distance over a dagger, with a 40 dmage spell is game chaning...
Her passive still exists, if I kill you I still get full reset on all spells and do the whole combo on your face, so please...
You don't need fast reactions, you're bound to slow down from a game mechanics here, not your own. I can do my combo atm in 0.4 seconds, after that I'll be forced to do it in 1.2 seconds minimum, which wont be my fault.
Her old combo is Q and correct timed E and W, so you can land full damage together with ult, otherwise you might miss the Q mark damage or cancel your ult with W... It's all timing and you actually need to have faster reflexes and thinking because you got LESS Period to think over of what you will do the moment your enemy dies... while now you got longer time to think, because the spells work slower than before and they force you to waste more time on thinking.
Do you actually wanna argue with an 8 years of Kata main, with your nearly no experience as her? Honestly?
P.S hating champions to play passive vs you in lane, means that you should stop laying Yasuo, Annie, Syndra and other bullies like them...