Miss Fortune is my main and she is a good champion. Just got a 28/1/11 game with her (although we did lose, unfortunately.) Her Q is very useful. Max it first and use it attack enemies, it will be your main weapon. Use your W when you want to get an advantage in fights. In pretty much like every other stat-benefiting W. Her E is useful for crowd control. It is also good as it outranges most opponents and allows you to chip them. Get a damage build so you can destroy minions, and then get a few health items, although you can switch this out for other items also get a speed item. It's helpful to dodge skill shots, so I use it, but some people prefer focusing on dealing damage or getting more health, its your preference. Like all champions she has counters but what I do is get my other teammates to attack my counters while I farm. None of her counters actually totally shut her down so as long as you play skillfully you can win. Her R is probably the most broken ultimate when your at a high level with damage items, but its not a no skill ulti because if your opponent is not caught in it, you just wasted mana and your ultimate, and your probably about to get killed becasue if your pponents not caught he/she is attacking you while your exposed, and its not like MF has a lot of health(unless she's level 18 in which she's invincible.) In terms of mana. For mana, you could buy a mana item but i focus on leveling because once you become level 5+ it doesn't become a serious problem anymore. And as with almost all other champions her level 18 is OP.