TOP: No matter who you play, there's always the problem of being camped, which is the top lane special. There's nowhere to run to if you get dove under tower, so there's an all-round con. Irelia has great sustain and is very powerful when she has triforce, but can still be squishy and kited before that. Trundle is a great duelist, but he doesn't do too well against ranged champions, and he has no definite sticking power, aside from a well-placed pillar and W.
Jungle: Zac is strong, but needs team cooperation to work. Rengar is strong and can one-shot people, but is only good at that, and not very effective in teamfights unless you get really ahead.
Mid: Ahri is good, has good mobility, and AP-scaling true damage to supplement her weak overall burst damage. Can be easy to fuck up CSing with her, though. Syndra has less mobility but a very safe laning phase and strong burst overall. Really strong pick, actually.
Support: Alistar and Leona are pretty much the same, being CC-heavy beasts. They can be kited out with ranged champions, but their engage is quite good. No real cons, afaik.
They're all very fun, imo.