Tips on Twisted Fate?

Don't try to win your lane, try to win the other lanes

This is just my opinion.

1. When in lane, start with a point in W. This will give a little bit of harass and grant you mana when you need it. Choose your card: blue for mana, red for mini AoE crit, or Yellow for stun depending on the match-up/situation. Blue does the most damage.
2. Level 2. put a point in Q. This will help you farm. Remember your blue card when you get low. 3.Start with and . Level three point in W. Level 4 point in Q. Level 5 point in E. From there, I try to max W first, Q second, and E last. Put a point in R when it comes up.
3. First back, try to get and . This will give you a little more punch and speed. The on-hit effect from the Sheen procs when you choose card, making your next AA hit harder.
4. Don't forget to keep an eye on your enemy's build using [tab]. If he is using MR, pick up . If they are not building MR yet, hold and get for early CDR. If you have enough gold, pick-up . This gets you closer to , which works well on TF.
5. For more CDR, you can go . By this time, you should have 30% CDR with three items.
6. Go for . The last two are situational based on who you are playing against. If you are facing a lot of ADCs (God hope not.) and into . This will also work on people building MR. You can also forgo the Scepter if they are MR heavy and add . If you are happy with the pen before the , pick up for more AP.

I use hybrid pen marks, armor yellows, 6 magic resist blues and three CDR runes. I use three AP Quints. TF does both magic and physical damage. This will help a lot.

Keep in mind, I am not a ranked player. This is just what I do and it seems to work for me. I am sure there are more experienced TF players out there.

Oh, there are videos on YouTube that can help you as well.