Shyvana's Dragon form E passes through the target at this precise range
If you're exactly this close to a target (close to half of her max auto range) with a small hitbox, your empowered E will go right through your target like it's not even there. Noticed this on a dummy and confirmed in a custom game on Teemo. I don't think this would work on a champion with a larger hitbox and haven't tested anything bigger, but there are enough small champions in the game for this to be broadly applicable. What seems to be happening is that her head is launching the projectile from the other side of her target, but if you step an inch closer than this it detonates as usual. Furthermore, if you hug the target and get range to ~0, your E detonates in a 360 degree arc, no matter where you aim, it hits. Getting this to happen is really precise and took me a while to replicate it (I think it's some exact range value that causes the bug), and I've never had it happen in a real game, but it could conceivably have a big impact if you're building AP and ought to be fixed regardless.