Camera Focus Bug
Numerous people are going to claim that this is not a bug, and it is working as intended...
Alt-tabbing out of the game, upon re-entry, quite often the camera will lock on to my champion, and there isn't anything that can be done about it, except for exiting the game and re-joining it that will remove the bug.
This is annoying as hell, as 90% of the time I don't have the time to wait to relog into the game, don't have the time to send my champion to base, etc etc.
And no, the in-game keybind to un-focus the camera on/off the champion does NOT work. (Derp, it's a bug)