Nasus W Bug
In a recent game I was playing against a Nasus top lane and while the effect of his W is supposed to SLOW auto attacks, every time he cast it on me it would outright cancel them (and yes, before anyone asks, I made sure to check that I wasn't canceling it myself by right clicking away from him after the first few times it happened).
It gave him an extra free hit on top of the extra blows he gets from W's intended effect and on Nasus that was enough in more than a few instances to turn the tide in his favor.
Please look into this.