Support Rune Page

well....the easiest set up in my opinion would be

Hybrid pen reds. Armor Yellows. MR Blues And movement speed quints.

You can vary it quite a bit...but generally the armor and MR are fairly standard. Depending on what supports you like to play...you can vary it with straight magic pen reds and some AP quints as well.

in order of my preferences,

Marks - Hybrid Pen, AD, MP Seals - Armor Glyphs - Magic Reist Quints - Gp10, Armor, AP, Health

are all good choices.

Marks: Hybrid pen are quite good for many situations and are quite versitile, MP are good for your AP supports, and i mention the AD for doing damage to turrets, a few supports have AD scaling but that's about it. the AD is a bit more of a niche pick for me.

Quints: i like to run Gp10 on many supports for a steady gold income and to get that sightstone sooner than the enemy. AP-MP is one that i'll use on supports and mages in any position, Armor is good for AD heavy team comps or if they are running an AD kill lane bot, Health is good vs. an AP kill support like annie and health is good for every champion in every role and is imo the most versatile rune in the game.

Depends on the type of support really

for disruptive damaging supports like Annie, Lulu, Karma, ect. I tend to use Marks: Magic Penetration Seals: Flat Health Glyphs: Flat Ability Power or Scaling Magic Resist Quints: Flat Ability Power

Tanky supports like Thresh, Leona, Braum, ect. I use Marks: Flat Attack Damage Seals: Flat Health Glyphs: Scaling Magic Resist Quints: Armor

I have used other set ups as well, such as Gold per second Quints and Seals Scaling AP or Movement Speed Quints

There's really just a lot a viable options, it all just depends on what you think you'll need and how it fits your playstyle. Either early game (like Flat AD, AP, Armor, MR, ect) or late game (scaling AD, AP, Armor, MR, ect)

defensive runes on support are very versatile, and can be used on pretty much all of them. if you have the ip, get hybrid pen reds, otherwise you have the option of just taking armor reds if you have lots of ip you can go health yellows, otherwise just go armor yellows some supports may gain from having 3 flat mana regen glyphs, if so get those and then the rest will be mr scaling for defence, flat armor, or sometimes ap. quints, i prefer 2 hp and one armor. but sometimes I can plull off something like mana regen quints.