I'm upvoting this for Karmic Karma, mostly. I'd be neat to have an ultimate skin that can be constantly changing forms depending on totally outside factors such as K/D/A, cs, etc.
But lets try and expand on it even more!
If you're going to use the concept of Karma for a skin, let's play around with chakra colors (or aura) for even more effect than classic light/dark. Something that can change depending on your best in-game contributions. Something along the lines of maybe...
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Take a combined 10+ objectives (Dragon/Rift/Baron/Towers/Inhibitors): Purple - Crown (divine power) chakra
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Obtain a vision score of more than 50: Blue - 3rd eye (vision) chakra
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Heal or Shield 15,000 damage: Green - Heart chakra
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Buff allies/debuff or crowd control enemies for a total of 5 minutes: Yellow - Solarplexus (control) chakra
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Obtain 140 cs OR gain 1,000 gold from your support item: Orange - Sacral Chakra
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Contribute to the takedown 5 enemies: Red - Root Chakra
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Bonus 1 - Max Q first: Black (Eeeviiil!!!)
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Bonus 2 - Max E first: White (protector!)
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Or keep your neutral tone by maxing not having either maxed before lv 11
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Karma starts off mostly colorless - with her clothing taking on very muted, gray-ish tones.
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Karma's bonus colors will likely be among if not the first she unlocks, and will overlap with other colors to give them a brighter or darker tone (if you're damage-centered, you gain the dark bonus, if you're shield-centered, you gain the light bonus)
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Completing each little mini-game grants a form change that gives her colorful changes in the game. Each of these will rank upwards (red -> orange -> yellow and so on)
Now that I've went this far...this will probably not happen. Mainly because it's a lot of coding for the dev team. The design team could probably make this work pretty easily by just splashing the color pallets around a bunch in a copy/paste sort of fashion...but the actual coding on when to change into one of...let me do the math here...21..? different colors (even more combinations than Lux!) would likely be a nightmare. And to try "choosing" these would be an even bigger nightmare...though I suppose you could cycle your unlocked ones with ctrl+f5..? Keeping the light/dark of course, but cycling the color scheme.