Super fun, interactive bot lane, Lux + Varus

Something me and my friends have done. I mean, I don't know if it is good out of lane, but in lane it's dirty.

For Lux, take dark harvest, cheap shot, eyeball collector, ultimate hunter, presence of mind, coup de grace with double adaptive force and armour/ MR for the last shard. Build spellthiefs, upgrade once then build full AP (ludens, deathcap, etc), maybe Athenes. For Varus, pretty much the same, you can swap out presence of mind for triumph but the lower cd on his ulti + mana refund is nice. Varus builds normally.

In lane, just poke for level 1. At level 2, if Lux can snare some one you can probably kill them, but don't overcommit. I'm sure you've seen where this is going though. At level 6 is where the enemies will not want to play anymore. The moment Lux snares some one, she hits her E R combo, with Varus using W empowered Q. Dark harvest should proc for both of you and the enemy should be one shot. If Varus snares some one with ulti, same deal. Generally I've found pre level 6 to be decently threatening as well, but without Lux's ultimate you can't 100 to 0 them.

Eventually Lux will scale to the point where she can one shot people without Varus. Try not to throw away your early snowball as you should both have some pretty hefty bounties. Even if you can't push the lead into the late game, you just had 14 minutes of one shotting people, which can be pretty funny. The damage goes off so fast, they will not be able to heal through it. Provided you can hit skillshots of course, and that they don't pick Morg.

Warning: If you do this enough, the game becomes extremely similar and the fun will drain from it as the novelty wares off. Proceed at your own risk.