Zoe is broken with current Conqueror
EDIT: Yes I realize you have to be in combat, Zoe is ranged and can dive in and out with her ult. She can do just fine staying in combat to wait for the Rune to trigger. I have access to PBE and have tested it myself.
"[EXPERIMENTAL] After 4 seconds in combat, your first attack against an enemy champion grants you 10 - 60 AD, based on level, for 4s and converts 20% of your damage to champions to True damage for the duration. Melee Only: Damaging enemy champions refreshes this buff."
Zoe is just one champion who will greatly benefit from this. The true damage it converts is all damage you deal, which includes magic damage. This means a well rounded Zoe player can start one shotting tanks because why not. In its current state the rune will cause unintended negative effects. [sg-zephyr]