same story over here, i tried several things to fix it but none of them worked...
maby this will work for you:
HOW TO FORCE A REPATCH:
Go to your Riot Games folder (Default path: C:/Riot Games/League of Legends)
Open the following directory:
C:\Riot Games\League of Legends\RADS\projects\lol_air_client\releases{highest version number}
Delete the following files:
releasemanifest
S_OK
Open the Deploy folder
Delete the following folders/files:
lib (folder)
META-INF (folder)
mod (folder)
lolclient.exe (file)
lolclient.swf (file)
locale.properties (file)
Restart League of Legends
(sorry for poor english..)