Jayce Bug
I noticed this a long while back, but I thought it was something obvious. Apparently not, because it still exists.
While Jayce is in Cannon Form, right before he autoattacks someone he can switch to Hammer Form and keep the ranged attack while still having the explosive nuke of the Hammer's magic damage. This allows him to easily harass and, if done properly, he can land that empowered autoattack after Hammer E'ing a champion away, leaving them with even less health and no way to trade back.