Some assist for the resolution?
I have a 1280x1024 monitor and with that in the game the same resolution, just tried TFT and it was kind of messy, I mean the interface and all, some letters over my little legend (something like assassins fighters and all that classes), that I couldn't even see the items, thus didn't know that's how I am supposed to use them (basically items didn't exist for me the whole game). Maybe you could scale it down a bit, smaller everything except the game, can't even see the whole map because of the screen where I buy champions. Really don't want to lower the resolution if that would even help!