Who is in Mind of The Virtuoso?

That's what I was thinking as well! I'm not too sure about the Garen one, but I figured it must be him since the man with the tree is probably linked to Zed since it was his poster that had the tree/flower thing from his eye... I'm also uncertain about Vi, but the smoke one is clearly Sona, so I just filled in the blanks... Do you maybe have any evidence or proof? Because I'm really digging the idea- heck, it was my assumption as well- but I'd just love some facts to solidify all of this.

The woman in the beginning seems to fit with Vi, despite the lack of gauntlets, though with the teaser image she was depicted with the gauntlets breaking apart. The hairstyle fits, though. Also worth noting that the bright embers from her animated icon fits with the burning flower aesthetic shown in the video.

The shot of the feminine lips is Sona; it matches her teaser image, and there are butterflies flying in the smoke, just like in her champion icon on the site's Champion page. What's interesting is that Jhin's actions allowed Sona to speak, because she was able to utter a sound.

As for the two male figures, they're more than likely just be random figures depicting how Jhin's gun works. The bald man was shot in the head, with a bright blue light emerging from his mouth. He had no armor. Garen, on the other hand, was shot in the heart, and his armor was pierced through. The final man in the trailer sprouts a full tree from his body; however, Zed's teaser image sprouted a branch of cherry blossoms from the visor of his helmet. It's a pretty big difference.

These guys are getting shot with the same abilities,but in the end they don't fit these champs.

I mean as you say,the second guy is bald,so it is surely not garen and the first woman has a different hairstyle than VI. The last one also seems a bit too muscular for Zed.