They possibly could!
Look at Arclight skins and Guardian of the Sands, also Eternum!
I can envision an Omega Squad Tristana skin (975 or 1350 category) with particle changes and a gun model change. Like her main gun be a LMG and her E makes her grab a grenade from her waist and throw it. Her ult could be an anti-tank or surface to air rocket launcher on her back. Kinda like Jinx.
Omega Squad Corki!!! He flies a freaking F-22A or F-35A!!!!! OR an AC-130!!!!!!!!
Omega Squad Rumble!!!! He wears an exo-suit similar to the ones in Call of Duty, Edge of Tomorrow, or Avatar.
Omega Squad Ziggs... His Q makes him call in an airstrike, so instead of seeing the bouncing bomb you just see small explosions and when the bouncing bomb actually hits someone then a larger explosion occurs. His W would be similar to his current one. E would make him throw claymores. His ult you hear him make a call followed by a confirmation then fractions of a second before his ult hits you hear and see the shadow of a B2 or F-117 flying overhead then the bomb strikes. Oooh! The designated area could be a flare with red or orange smoke!
Rito are you paying attention????