They are completely different champs, so without knowing your preferred playstyle it's hard to give that sort of advice.
Cass, while she has fabulous sustained damage and an ult that can really set up a teamfight, she'll take a lot of practice before you really get good at her. You have to get used to watching your target to make sure they're poisoned for your e reset, the q has a delay that takes a decent degree of predicting, and she doesn't really have a reliable escape. She is not a burst mage, and trying to play her as such will result in your death.
Darius is a ad slaughterfest, able to do damage while still being a bit innately tanky. He is the cleanup crew, but like Cass has low mobility and a bit of a learning curve. He has few difficult matchups, and can deal out the damage, but also be prepared to deal with people who will bitch you out for ulting someone as a "kill stealing jerk"