Dodgeball Syndra
Seriously, have her in gym clothes with those big red rubber balls floating around her. It would be great! When she ults she could blow a whistle and point at her target as all the dodgeballs hit them (or conversely yell DODGEBALL!). Just think of the distinct noise those big rubber balls make! I would buy that skin in a heartbeat. Also, bonus points if her joke is the 5 d's of dodgeball (those being dodge, duck, dip, dive and dodge).
"If you can dodge a wrench, you can dodge a ball!"