Keep an eye on your ward timer! I've found it effective to ward around the time that the second ward trinket charge is halfway done charging.
Play around the side that you have warded, and make sure to not overextend for CS.
If the enemy laner is being aggressive, back off, let them be aggressive. <--- this'll take some practice, and you'll get better at judging when and when not to step forward to either farm, poke, etc.
Pay attention to how the lane is moving. If the enemy is pushing, you're probably fine to be aggressive on the side that you have warded. If they're freezing or moving back towards one of the sides, don't match their movements. Back off, stay safe.
For Orianna, ward on the other side of walls for engage-heavy junglers. She's super squish and is only able to escape through flash, ghost, W, cleanse possibly.
For Morgana, stay safe and use W to farm, don't try to be aggressive, just get items for lategame.
For Karma, be aggressive. (Change of pace, huh?) She has more than enough CC and escape to get away with being aggressive, and as a utility laner, is able to function on low gold income. So if you die, or if you are denied CS in return for being aggressive, or are camped yet don't die? Just get an item or two and you'll be okay for mid to late game.
For Ahri, farm farm farm. Get picks. P R A C T I C E. Never engage without some type of spell to follow up your first spell. CDR never hurts. Again, play on the side that you have warded and don't be afraid to either deep ward or roam bottom/top. She's great at roaming, getting picks, and helping junglers.
For Annie, play around your stun, and always always always make sure you have Tibbers up in case things get sticky. Never play further than the halfway mark of midlane. You have zero escape. Remember to ward the brushes, using the tip that I first stated.
For mid in general, just start to farm, keep your distance, and gauge how your lane is going to go. If things get sticky, don't be afraid to ask for jungle pressure to farm, to help take tower, etc.
Expanding your champion pool might help as well. ^_^