I would really like to see League of Legends with a touch screen interface, but I believe the problem really comes down to 'key bindings' and the fact that there would really need to be too many things tied into the interface that would make the HUD too cluttered. Navigation would be really smooth with gesturing, but everything like, movement/attack commands, pings, summoner spells, using different abilities, different targeting methods, interacting with shop, ... I mean ultimately it could be done, but it would be a chore. .. and to continuously develop for a game on two very different platforms, involving different interfaces, ... sounds like a nightmare.