What I Learned From Team Builder....
...is my new favorite build:
Aggressive, harass/gold generation support Ashe:

9/0/21 with gold per hit mastery. AD/armor/mresist/gp10 runes (you might prefer other runes tho)
->
->
/
- Late Game ->
/
with boots in there somewhere and lots of early potions (with the biscuit mastery :D )
I went 5-0 of the 5 games I had time for on TB. Here is an example game. note the gold. you generate a lot of gold.
Early lane presence is insane. And once you're ahead, your cc is crazy at catching people for snowballing your ADC. And did I mention you generate a lot of gold? Also, tower pushing...wait...what tower? that's right. It's gone already!
I'm calling sleeper OP on this one.