Unsealed Spellbook Will be Meta Pick for Top and Support
In my humble opinion, I believe that "Unselaed Spellbook" (UnSp) cornerstone Rune, will become a top lane meta pick, and these are my reasons.
Revive and Teleport, are and insanely powerful teamfighting combination. Urf mode, when if was first released, provided enough evidence of this, but of course they worked so well, because the cooldowns were so low, that Riot had to remove this combination, by getting rid of Revive in this gamemode.
But the combo will be even more powerful with this Rune during ranked games, so much so that it will be a MUST PICK for top laners and supports.
Top laners usually provide the team with valuable initiation and front line capabilities. But they also die.
Revive is the most useless Summoner Spell for the first 30 or so minutes of a game. But after 30-35 minutes, it becomes so insanely valuable. Being able to swap it with flash during the late game, is awesomely good.
Imagine this scenario; after 35 minutes, there is a teamfight around Baron. Your top lane Malphite goes in, but gets destroyed, but you manage to also kill one of their guys; so it's a 4v4, no big deal. But your Malphite has UnSp, and instantly revives, and teleports back to the fight. This is like a guardian's angel, but WAAAAY better, because you have full health/mana. This single rune just changed the entire format of the teamfight so that it's now essentially 6v5.
I think this will become so meta for top laners, especially in the proscene, that riot will eventually have to change it somehow.
If your enemy top laner gets it, but your top laner doesn't, then your team basically can lose past the 30 minute mark.
The argument against this is that it's a lategame thing. That you give up other, more aggressive Runes that can essentially snowball a game. But this is a bruiser/tank/initiator pick. So a teammate could take it mid or even jungle. But the meta will be at least TWO of your teammates will need to have it, especially one of your front line guys.
Anyway, I've rambled;
TL;DR - This rune gives your team an EXTRA PLAYER during late game team fights. This will be insanely valuable since the enemy team will have to kill you TWICE just to win, and THREE times if you have guardian's angel, and FOUR times if you're a champ with a revive passive (Hahaha, just imagine this shit on Aatrox or Zac!!!!)