Anti Attack Speed Rune
Really wish we could have one. AS champs that can abuse conquerors are absolutely monsters. It would even help against champs like irelia. Or champs like vayne, Kai, etc who abuse rageblade to no end. It just feels like the few options that exist actually blow and other defensive poor scaling runes seem to be of little help, especially with the current level of true damage. Some kind of rune that slowed enemy AS by like 10%, or if it simply reduced Auto damage by a certain percentage like ninja tabi, I dunno. Just throwing it out there to be considered and fine tunes by people more knowledgeable than me.
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's R stops making him immune to attack speed reductions. %health true damage autos are bad enough on Vayne, but at least she can have her attack speed slowed as a counter