Vayne balance suggestions
I don't have a lot of experience with Vayne but i saw on some post that people didn't have problem with true damage from champs like Darius or Cho'gath becuse they where melee. And i thought that a nerfing her true damage at long range was a god idea.
I was thinking that if she is at her full aa range her silver bolts damage could be X% magic or physical damage instead of true damage. If she is closer to her target when the silver bolts proc she will do more true damage. You could maybe even decrease her true damage further outside her aa range to make dashes more effective against her (more counter-play).
This would make harassing her more worth it and therefore reduce her early game potential, which is something that i think players would like.