Warwick getting screwed even more with the preseason changes.
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Mana pots are getting removed. His early game is terrible and this will hurt his laning phase since he needs mana to be able to sustain enemy harass and survive.
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Wit's End nerfed. Almost no one buys this item but it is core on Warwick as it increases his damage output (passive,Q and R) significantly.
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Grievous Wounds and QSS on every ADC. This means his ult and team fighting will be less efective since he has no defensive steroids and the only thing that makes him durable is his sustain.
So basically his laning phase will be painfully bad, his damage is going to be lower and his team fighting will be worse.