Since Lost Chapter may be coming back....
Could we get some version of Pox Arcana back?
When Bilge water Brawlers came out, I enjoyed using this item and seeing the recent changes to mana regen items with some experimental others, this item would seem like a nice addition to add to the pot. The stats may need to be adjusted a little, but it may be a highly viable item for getting mana.
for those who are new to the game since the game mode has ended, or just need a refresher, Pox Arcana did this : http://leagueoflegends.wikia.com/wiki/Pox_Arcana
+100% base mana regeneration +100 ability power +20% cooldown reduction
UNIQUE – POX: Applies a stack of Pox for 10 seconds whenever you deal ability damage, stacking up to 5 times.
UNIQUE – DISEASE HARVEST: Deals 100 magic damage plus 20 (+5% AP) per stack of Pox (maximum of 200 (+25% AP)) to all nearby enemies affected by Pox, and restores 5% of your maximum mana for every Pox stack harvested. 60 second cooldown.