Rek'sia in Twisted Treeline
Not sure if many are aware of this, but in Twisted Treeline Rek'sai can tunnel from the map near alter to the inhib. This is very strong if the nexus tower is destroyed, as she can backdoor with ease. In addition to little time to respond, if you don't quickly kill her or chain cc her to death, she can just tunnel right back out to safety. Along with the short tunnel cooldown, this effectively traps an entire team in their base while the rek'sai's teammates can farm or get a free vilemaw until they can push to win.