well lets see...
Just to get this out of the way Zyra Release was a patch that happened in 2012 of July. It was also tied with Twitch's Rework for his kit. His Visual Update occurred in 2014 of April. So before Twitch got nerfed in Patch 4.10 but after the Zyra Release Patch, he was relatively untouched, getting QoL tweaks, for OVER 2 YEARS.
Now lets get a look at the damage done:
#1) Twitch's base damage was nerfed from 52 to 49.
#2) Twitch's Passive (Deadly Venom): Originally before his rework update (Zyra Release) was 2.5/5/7.5/10 then it got nerfed to 2/4/6/8 and then further nerfed to 1/2/3/4/5/6
#3) Twitch's Q (Ambush): Originally before his rework update (Zyra Release), there was another patch. The duration of his stealth was reduced to 10/20/30/40/50 seconds from 20/30/40/50/60. Then when his rework occurred and his stealth was reduced further to 4/5/6/7/8 seconds and +20% movespeed while stealthed.
THEN if that wasn't bad enough for his Q they go and nerf the stealth delay from 1.25 seconds to 1.5 seconds AND the stealth delay while taking damage went from 3 seconds to 6 seconds.
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I could go on and on about the rest of his kit but lets just say that the actual buffs to his kit from the Zyra Release patch pales in comparison to how they nerfed him and keep nerfing him.
What bugs me so much is that I personally don't get RIOT. What do they want Twitch to do?