No viable keystone options for Vladimir
Everything in the precision tree is obviously AD/Attack speed based,
Electrocute in the domination tree won't work as Vlad has a difficult time hitting reliably with 3 abilities as his typical combo is an E followed by a Q. This would require me to throw in an auto attack into the mix which feels wonky and unnatural to have to change his playstyle, in addition to the facts that his auto attack animation is really slow and has a really short range (much shorter than both his abilities). It's not good to W for damage so that's out of the question and my ultimate has a 4 second delay before it actually deals damage meaning that unless I ult first (therefore giving my enemies a massive heads up) then I won't really be able to reliably proc this effect. Stormraider's Surge, which is my current preferred keystone, as it doesn't require 3 hits but 30% of my target's health within 5 seconds is a much more reliable alternative for him than thunderlord's. The problem here is that the new "surge" replacement, i.e. "Phase Rush" from the new sorcery tree activates the same way as thunderlords/the new "Electrocute", which as I have just explained above, is unreliable for Vladimir.
The rest of the domination tree is for junglers obviously.
Summon Aerie is a support oriented keystone, and the comet is best suited for long range mages or those with hard crowd control such as Lux.
The inspiration tree is obviously support oriented and the resolve tree is for tanks with crowd control or supportive capabilities.
Please consider changing the way Phase Rush is activated. The way the current version of that keystone works is perfect for Vlad as he cannot reliably hit an enemy thrice within 2 seconds, but damaging a large portion of the enemy's health within the same time frame would work much better.
Aside from Vlad I feel like many of the new keystones are lacking options for other champions as well.