Critical: Champ Selection UI Bug
There's some kind of UI bug that's making you go into games with the wrong runes or masteries. This has happened several times to me, so far, and while I at first thought it was just my imagination I began checking my runes and masteries through another site while in-game, confirming that they were actually incorrect. Also, after starting another queue and joining another champ selection, you'll then see how you have the wrong runes or masteries selected as it'll be pre-loaded with what you apparently were using last-game. And again, despite switching them to be what should be the right runes and masteries per your labels, you'll end up with wrong runes or masteries again. I had a friend second this as happening to him also.
This is a critical issue, Riot. This needs to be fixed ASAP