Error saving settings during champ select causes runes to be deleted.
This evening I was playing just before 8:30 PM PST and my champ select was cancelled at 20 seconds due to a bug saying my selection couldn't be saved due to an error. I hadn't changed my rune pages for over 1015 seconds and editing hasn't been done for close to a week. I got into another champ select and had no issues and all seemed well.
Just before 10:30 PM PST I launched the client again loaded into a champ select and noticed it was on one of the default runes, I went to change it and all of my rune pages had been deleted by the client. The only pages I had to choose from were the preset ones and I had no time to make new ones. After the game was over I looked and sure enough there's nothing there and no option to restore all my rune pages.
This seems to related to the earlier client issues giving that error when trying to change runes but now instead it deletes them completely once you exit the client. :(