Runes Not working

Some of the runes don't seem to be working on some champions. i played syndra and sylas. mana flow band didn't work on either of them. and electrocute didn't seem to be working on syndra or akali in the matchup. Also, transcendance (or whichever one grants 10% cdr) gave me the cdr late, like at 12 or 13 minutes. but the bug with mana flow band is really cuking mages and anyone who tries to take the rune.