First Game: Runes got resetted to "The Colossus". Champ Select showed other Rune page selected.
Patch Notes: "Champion select dropdown menu now remembers your last selected page. No more "The Colossus" rune page every game."
I played my first game on the new patch and, according to the Patch Notes and my Champ Select, I had (automatically) selected my Precision Runes for my game with Lucian. Makes sense since I used them last time and because they now get remembered by the game. Ingame I noticed that I didn't see my "Press the attack"-Marker on enemies when attacking them. When checking my runes I noticed that I somehow had the "The Colossus"-Runes. First I thought that maybe I had somehow just misread my Runepage-Name and maybe I had played a Tank in Aram last time, but when I went into the next Champ Select where I got Vi, I still had Precision-Runes as my selected Runes.
When I then opened the dropdown for the Runes, I noticed that somehow my Precision-Runes as well as the Resolve The Colossus Runes where ticked (as seen on the screenshot). I don't think that this is intended :P
(It got fixed after I changed my selected Runepage for the first time this patch, but still that shouldn't happen.)