Super Galaxy Kindred and those flashy autos.
With this particular skin, haven't noticed with the others that she has, the issue I have with this skin is when it comes to getting stacks. The more stacks, the brighter and flashy her auto attacks become. With more attack speed, the more flashes there are on screen.
The constant flashing from the autos prevent me from watching the screen, which ends up with me not engaging or joining team fights to avoid head aches and other issues it causes.
I did at first contact support but they told me to post on the boards so I hope someone who works with skins sees this. :C
Edit: I have checked out her base and it has the same issue but not as bad though still troublesome.