think about it . the smell alone would be off putting, but then you are drenched in it would probably make you gag . think about how bad it would be for warwick and rengar to have to gank him and he throws a venom cask. but the real problem is after every fight with him you would have to buy new armor because you probably cant get that smell out. just my opinion
Get Nami to wash him then https://pbs.twimg.com/media/BGAIO2OCQAAm0oH.jpg
Probably pretty comparable to the humiliation of being killed by a dude throwing playing cards 
idk, i smell bad without twitch's stank, id say the most traumatizing champs to fight would be 
, being licked a bunch of times before being swallowed and spit out over and over is scarring, as is having your soul ripped out of your body and being raped hentai style by a bunch of tentacles
