Unfortunately you're not giving much to go on right now, so, I want you to do 3 things:
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Repost in Help & Support
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Look through The Wrenchman's Toolbox and try to find what sounds closest to your specific problem. Try implementing the proposed fix.
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If all of that still doesn't work, download and run a Netalyzer Scan and post the results in that Help & Support post you should have up.
Keep in mind things like:
- where/when in the game you crash
- whether or not you can get to the AIR client (orange 'reconnect' button and all) before problems occur again
- what ISP you have
- your computer specs
All have the chance of being very helpful. Anytime anyone's troubleshooting, the one trying to help has to get a specific problem out of an infinite number of thing that could go wrong and for that we need info.
If you would rather just skip all the public discussion, then you could also just submit a support ticket to get a 1 on 1 with a Rioter for them to try to help you.