Breast Cancer Awareness Summoner's Rift

No, let's not. No reason to start making variants for all the non-profits in the world. It'd just be a reason to not play that map. If you want to donate to a cause, fine - you can do that already. Keep that offline.

why not prostate cancer awareness?, it is way more needed and deadly

Good intentions, but I feel there are better ways for Riot to support the cause, such as an Icon or a Ward and donating the profits from it. Making the whole map pink would just be distracting for the players in my opinion.