[GamePlay] Camera permanently locked, Can't left click with mouse - Mac

After loading into a game, I cannot move the camera by moving my mouse to the edges of the screen when using 'unlocked camera'. The only way to move the camera is to hold down the space bar to allow the camera to follow my character. Additionally, whenever this bug occurs, I am also unable to left-click to open the shop or select/drag items around my inventory. The only fix to the problem that I have found is to leave the game, kill the LoL client, and restart. It seems to get rid of both bugs since, after loading back into the match, I am able to play without any problem. Unfortunately I've been penalized by LeaveBuster a few times for having to quit and load back into so many games. It does not happen often, but once it does, it reoccurs in every game until I exit the LoL client and restart. Please help me out as this has been going on for quite a while.