My settings got reset and now i cant quick cast

Just change them back?

I have the exact same problem right now. I have no idea what it is or how to fix it.

Incidentally, is your space bar goofed up too? Mine goes to per-side offset instead of centering on the champ right now. It's really annoying having to play locked screen due to that...

Try deleting your config folder and open up a Custom game and change your settings. You can just delete the specific files you need (input.ini or game.cfg), but you must also do PersistedSettings.json too.

Didn't they introduce some new default in settings a few patches ago that messed with this? I can't remember what it was though.