Renekton Left Click Disabled

When I play Renekton, several times through the game the left mouse button stops working. Usually the cursor will turn from the normal hand icon, into the targeting icon. I have not yet figured out if there is a trick to reenable the left click, but it does start working again after a minute or so.

This does not happen with any other champ that I have noticed.

It is easily reproducible for me.