Everytime I go into a game, my hotkeys don't work.

Everytime i join a game whether its a normal, a ranked or an ARAM my hotkeys do not work. I've tried repairing, switching computers and accounts and it still happens. This requires me to exit the game and join back hopefully just in time before minions spawn. But in other cases, it takes 3-4 tries of exiting the game and reconnecting. By this time, the enemy laner is 4-5 levels ahead of me and i already lost lane. This just cost me a ranked game and I am very salty over it. Please fucking fix this.