Always Something

After the .11 patch for this season i started noticing a problem with my mouse during match of league. i'd say roughly 20% of my right clicks during matches were not registering in the game. The mouse is brand new. It works absolutely everywhere else other than ingame. It even works on the league home screen. But its not working ingame. I've looked it up and only found that other people have had the same problems in the past. But I havent found a solution. And i've spent money on this game; not a lot but enough for me to say that if i stopped playing it'd be a waste of my money. and riot has such a good fan base i'd like to think and i know you guys do your best and i know that none of these bugs are intentional obviously. it just seems like its always something. In addition to the solution for the ingame problem im having, if you guys had something that might help during patch loading to prevent these problems i'd appreciate it a lot

-thx