[GAMEPLAY] Mouse seems to stop working at random points

I got a new mouse, and it works perfectly fine. I've been surfing the Internet for a while with it, and right as I start playing some games on League, for some reason, it stops functioning at random points. This frustrated me, but am I the only one getting this problem?

I'm using the Mac Client, and this is the mouse I'm using. I've had it less than a month, and it's in good condition, so I don't believe the mouse is malfunctioning...if it was then I would be having problems right now.

Created a custom game, the mouse glitches out at random intervals. The mouse then reverts back to normal after is closed. It doesn't stop whenever I have the client open.

This has been happening ever since Patch 5.2 came out.