Doesn't really fit bugs or gameplay but: keybinds that can't be changed while in TFT
I use "bind auto attack click to left click" from keybinds while playing SR games. With this enabled, whenever I left click a champion to buy, it moves my little legend to where I clicked. This leads to the camera constantly moving away from where it should be, so I have to quickly click the champion to buy then click back on screen so it doesn't move away. Can be pretty annoying, and have to go into a a real game (normally just a practice tool game) to fix it because the option isn't available in the client or in a TFT game to turn it off. Either have this click not work in TFT or just have the option show in the keybinding settings to be turned off.
Edit: Found a way to fix it in client, just go to keybinds>player movement and unbind attack move click. Still stands that it can't be changed in TFT itself.