The relationships we see, I think they should have issues like benefits and working together.
Like 
/
both have couple of same matching skins and 
appearing on 
's heart seeker skin doesn't mean they are official relationship.
If LoL shipping is just a hint with no relationship in it, then it won't be a problem to you guys (and the lore).
/
both have high noon skins, just saying.
https://36.media.tumblr.com/21002ca6cdc34c8bca55131afe6e6711/tumblr_nbcn4tHWZx1tbpqalo1_500.png
The most mathematical bromance in League of Legends.
That seems more like a gameplay question rather than a lore question, some skins are just meant to be fun and funny, like Dr. 
and her paitent 
, it's humerous rather than signifying any relationship. Champions like 
and 
who have a rival/love relationship.... I like the little hints that we have gotten dropping their affection to each other, but I think it would be hard having animation or skill synergy between similar skins, taunts are a different story.
On an unrelated note, Hashtag AmuNie ftw 
These are the pairings I've heard of so far
x 
x 
x 
x 
x Cactus
/ 
x Bob Nashahago
x 
x 
x no one
x
x 
x 
x
x 
x 
x /
x 
(this one doesn't make any sense to me)
x
x 
x 
