Since we're on Demacia there's two champs I'm really wondering will be revamped...
and 
I'd love to see what they do with them; although, I don't feel like their lores will change much.
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Lucian was just born in Demacia. His story doesn't really impact it or shed much light on life in Demacia.
Vayne on the other hand (who does something similar to Lucian) has more impact on Demacia as she consistently lives there, is a noble so has some effect, and her story does bring up some of the tension between the Freljord and Demacia.
I'm guessing Xin Zhao will have his lore updated when they do Noxus.
And I think Lucian already got a lore-update during the Bilgewater event. He got a short story and they connected his lore with 
(Lucian saved her life so they teamed up together to fight the Black Mist) and 
(he was there wrestling the Kraken).
I want to know more about the Radiant order.
And possibly a new champion from them.
We'll likely get updates to these 2(as well as Sona) once they do a second demacia update.
And I think that Xins lore might change quite a bit,as he is on the VGU list. Lucians on the other hand is pretty much guaranteed to stay pretty much the same(albeit a bit expanded) as Sennas murder is mentioned in the Harrowing story.