http://fantasy.na.lolesports.com/en-US/news/fantasy-lcs-returns
If you don't have time to access the link:
One difference from 2016 that you should keep in mind is the new EU broadcast schedule. Not all EU teams will play two matches each week. If you draft Jankos to take care of the jungle for you, you should be in good shape in Week 1 as he is playing against Origen on Thursday and Splyce on Sunday. However, if you picked Trashy in round 3, you might want to find a substitute for Week 1 as Splyce is only playing on Sunday against H2K. Trashy will only give you one match worth of stats, potentially making him a worse starter than a less skilled jungler who gets to play two matches.
This adds a new level of complexity to managing your roster each week as you will need to add free agents and lean on your bench to make sure you get the most points possible.
We will be keeping an eye on how the EU changes impact this Fantasy split and we will revisit everything at the end of the season to see if we need to make any changes for Summer.
Essentially, yes. Drafting EU sets you at a disadvantage because you need to constantly trade out your players.